Key result
Mechanical ventilation caused a phasic variation in cardiac output of 10-50%, indicating that mean CO by thermodilution is best measured by averaging values taken at regularly spaced intervals.
Cardiac output measured by thermodilution during mechanical ventilation should be averaged from values taken at regularly spaced intervals due to significant phasic variation.
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Averaging thermodilution CO across ventilatory cycles may enhance accuracy in ventilated patients; animal data leaves open human confirmation.
Snyder et al. (1982) studied Mechanical ventilation. Mechanical ventilation was evaluated on Phasic variation in cardiac output (CO). Mechanical ventilation caused a phasic variation in cardiac output of 10-50%, indicating that mean CO by thermodilution is best measured by averaging values taken at regularly spaced intervals.
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