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January 1, 2008Vojnosanitetski pregledOpen Access

Myocardial hipertrophy in hypertensive patients with and without metabolic syndrome

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Key result

Metabolic syndrome in hypertensive patients significantly increased the prevalence of myocardial hypertrophy (75.4% vs 49.3%, p<0.001) but did not significantly affect left ventricular mass.

Why the study?

Does the presence of metabolic syndrome increase left ventricular mass and the prevalence of myocardial hypertrophy in patients with arterial hypertension?

Population

182 subjects, comprising 138 patients with arterial hypertension and 44 normotensive controls.

Comparison

Presence of metabolic syndrome (MetS) vs Absence of metabolic syndrome in hypertensive…

Design

Cross-sectional

Authors

BIBranislava IvanovićDCDane CvijanovićMTM. Tadic

Discussion

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Overview

MetS may raise LVH prevalence without increasing mass in hypertensives; leaves open independent causal effects.

Study Design

Type

Observational (n=182)

Structured PICO

Does the presence of metabolic syndrome increase left ventricular mass and the prevalence of myocardial hypertrophy in patients with arterial hypertension?

P
Population
182 subjects, comprising 138 patients with arterial hypertension (59 with metabolic syndrome, 79 without) and 44 normotensive controls, evaluated for left ventricular hypertrophy.
E
Exposure
Presence of metabolic syndrome (MetS)
C
Comparator
Absence of metabolic syndrome in hypertensive patients, and normotensive controls
O
Outcome
Left ventricular mass and prevalence of myocardial hypertrophysurrogate

Main Result

Absolute Event Rate: 75.4% vs 49.3%

p-value: p=<0.001

In patients with arterial hypertension, the presence of metabolic syndrome increases the prevalence of myocardial hypertrophy but does not significantly increase absolute left ventricular mass compared to hypertension alone.

Cite This Study

Ivanović et al. (2008) conducted an observational in Arterial hypertension and metabolic syndrome (n=182). Metabolic syndrome vs. Hypertension without metabolic syndrome was evaluated on Prevalence of myocardial hypertrophy (p=<0.001). Metabolic syndrome in hypertensive patients significantly increased the prevalence of myocardial hypertrophy (75.4% vs 49.3%, p<0.001) but did not significantly affect left ventricular mass.

synapsesocial.com/papers/6a3ff7a7901a52dbcb71b9f0https://doi.org/10.2298/vsp0811830i
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Metabolic Syndrome and Morphofunctional Characteristics of the Left Ventricle in Clinically Hypertensive Nondiabetic Subjects2006 · 47 citations
  2. 2Association of left ventricular hypertrophy with metabolic risk factors: the HyperGEN study2002 · 171 citations
  3. 3Metabolic syndrome and target organ damage in untreated essential hypertensives2004 · 187 citations
  4. 4Left Ventricular Hypertrophy in Severe Obesity2006 · 227 citations
  5. 5Metabolic Syndrome and Echocardiographic Left Ventricular Mass in Blacks2005 · 92 citations