Key result
Metabolic syndrome was associated with higher left ventricular mass and prevalence of left ventricular hypertrophy compared to hypertension alone (P>0.05).
Why the study?
The metabolic syndrome is associated with increased cardiovascular risk through left ventricular hypertrophy, but its role compared to hypertension alone is unclear.
Is metabolic syndrome associated with increased left ventricular mass index and left ventricular hypertrophy compared to hypertension alone in North Indian patients?
Cross-Sectional (n=50)
Is metabolic syndrome associated with increased left ventricular mass index and left ventricular hypertrophy compared to hypertension alone in North Indian patients?
p-value: p=>0.05
Metabolic syndrome is associated with a higher burden of left ventricular hypertrophy and increased left ventricular mass index compared to hypertension alone.
BACKGROUND AND OBJECTIVES: The metabolic syndrome (MS) is a condition associated with the clustering of risk factors including high blood pressure (BP), abdominal obesity, glucose intolerance, and dyslipidemia; which increases cardiovascular morbidity and mortality. High burden of subclinical disease component of MS contributes to the increased risk by causing left ventricular (LV) hypertrophy, thereby affecting long-term prognosis. This cross-sectional study uncovers the role of LV hypertrophy (LVH) and LV mass index (LVMI) in patients with MS in comparison to hypertensive patients. SUBJECTS AND METHODS: A total of fifty North Indians, out of which 25 subjects were cases with the MS (obesity, dyslipidemia, glucose intolerance/diabetes with hypertension) and rest of the 25 subjects were control with hypertensive patients were included in the study and assessed for LVH and LVMI by two-dimensional echocardiography. Data were analyzed by SPSS version 21.0 based program. RESULTS: > 0.05, not significant). CONCLUSION: MS, as a clustering of cardiovascular risk factors, is associated with higher LVM and prevalence of LVH. Therefore, high BP, increased waist circumference, dyslipidemia, and hyperglycemia separately and additively contributes to LVH suggesting that optimal BP control along with weight loss, lipid lowering agents, and euglycemic state may contribute to regression of LVH and LVM.
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Gupta et al. (2016) conducted a cross-sectional in Metabolic syndrome (n=50). Metabolic syndrome vs. Hypertension was evaluated on Left ventricular hypertrophy (LVH) and LV mass index (LVMI) (p=>0.05). Metabolic syndrome was associated with higher left ventricular mass and prevalence of left ventricular hypertrophy compared to hypertension alone (P>0.05).
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