Key result
An increasing number of metabolic syndrome components was significantly associated with progressively compromised cardiac structure and function, including increased left ventricular mass (p<0.001).
Why the study?
Is an increasing number of components of the metabolic syndrome associated with cardiac structural and functional abnormalities in adults aged 45 years or over?
Population
684 participants from a random sample of the urban population of Porto aged 45 years or over.
Design
Cross-sectional
Authors
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Metabolic syndrome severity signals possible cardiac changes beyond Framingham risk; leaves open causal inference and practice impact in cross-sectional data.
Cross-Sectional (n=684)
Is an increasing number of components of the metabolic syndrome associated with cardiac structural and functional abnormalities in adults aged 45 years or over?
Absolute Event Rate: 129.9% vs 100.1%
p-value: p=<0.001
Increasing severity of metabolic syndrome is associated with progressively worse cardiac structure and diastolic function, independent of traditional coronary heart disease risk scores.
Azevedo et al. (2007) conducted a cross-sectional in Metabolic syndrome and cardiac structural and functional abnormalities (n=684). Increasing number of metabolic syndrome components vs. Zero components of the metabolic syndrome was evaluated on Left ventricular mass/height (g/m) adjusted for age and gender (trend across 0 to 4-5 components) (p=<0.001). An increasing number of metabolic syndrome components was significantly associated with progressively compromised cardiac structure and function, including increased left ventricular mass (p<0.001).
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