Key result
A 1-year intervention of HIIT or moderate continuous training reduced carotid intima-media thickness in type 2 diabetes patients, but only HIIT improved peripheral arterial stiffness indices.
Why the study?
The exercise intensity that yields maximal adaptations on structural and functional vascular indices in patients with type 2 diabetes remains uncertain.
Does combined high-intensity interval training or moderate continuous training with resistance training improve structural and functional arterial indices in patients with type 2 diabetes?
Population
80 patients with type 2 diabetes
Comparison
Combined HIIT with RT vs combined MCT with RT vs control
Design
Randomized controlled trial
Follow-up
1 year
Authors
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Supports combined aerobic-resistance training in T2D; extends RCT evidence on intensity effects for vascular structure.
RCT (n=80)
Assessor-blind
1:1:1 ratio
No
Does combined high-intensity interval training or moderate continuous training with resistance training improve structural and functional arterial indices in patients with type 2 diabetes?
Mean Difference: -3.61 (95% CI -6.15–-1.07)
p-value: p=<0.01
In patients with type 2 diabetes, a 1-year intervention of combined HIIT and resistance training improved both carotid intima-media thickness and peripheral arterial stiffness, whereas moderate continuous training only improved cIMT.
Magalhães et al. (2019) conducted an RCT in Type 2 diabetes (n=80). Combined high-intensity interval training (HIIT) with resistance training (RT) vs. Combined moderate continuous training (MCT) with RT, and non-exercise control was evaluated on Carotid intima-media thickness (cIMT) (β = -3.61, 95% CI -6.15 to -1.07, p=<0.01). A 1-year intervention of HIIT or moderate continuous training reduced carotid intima-media thickness in type 2 diabetes patients, but only HIIT improved peripheral arterial stiffness indices.
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