Key result
Transient increases in mean arterial pressure completely inhibited 138 spontaneously active cardiovascular neurons in the rostral ventrolateral medulla of rats at 148 mm Hg.
Neurons in the rostral ventrolateral medulla of rats exhibit pulse-synchronous rhythms and are inhibited by increased arterial pressure, supporting their role in mediating baroreceptor reflexes and vasomotor tone.
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No immediate clinical implications for hypertension management; leaves open the translational role of RVLM neurons in human baroreflex control.
Brown et al. (1985) studied this question. Transient increases in mean arterial pressure was evaluated on Neuronal inhibition. Transient increases in mean arterial pressure completely inhibited 138 spontaneously active cardiovascular neurons in the rostral ventrolateral medulla of rats at 148 mm Hg.
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