Key result
HPeV-2 and HPeV-3 infections were associated with a 100% rate of viremia or sepsis upon admission, compared to 0% in HPeV-1 infected children.
Observational (n=28)
No
Absolute Event Rate: 100% vs 0%
p-value: p=0.001
A newly developed RT-PCR assay successfully identified and characterized Canadian HPeV isolates, revealing distinct clinical presentations and severity for different viral types primarily in young children.
No takes yet. Share an insight, caveat, or question.
May indicate higher sepsis risk with HPeV-2/3 in children; leaves open confirmation in prospective studies.
Abed et al. (2006) conducted an observational in Human parechovirus (HPeV) infection (n=28). HPeV-2 and HPeV-3 infections vs. HPeV-1 infection was evaluated on Diagnosis of viremia or sepsis (p=0.001). HPeV-2 and HPeV-3 infections were associated with a 100% rate of viremia or sepsis upon admission, compared to 0% in HPeV-1 infected children.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: