Why the study?
Iron deficiency anemia may induce cardiovascular adaptations and reduced iron availability may affect myocardial structure and function, motivating an evaluation of biventricular function in affected children.
Does treatment of iron deficiency anemia improve subclinical biventricular dysfunction in children?
Population
40 children with iron deficiency anemia and 29 healthy controls
Comparison
Children with iron deficiency anemia (pre- and post-treatment) vs healthy controls
Design
Prospective case-control study
Key result
Treatment of iron deficiency anemia in children improved left and right ventricular longitudinal strain and tissue Doppler parameters, though some subtle myocardial alterations persisted.
Authors
Loading...
Persistent subtle biventricular changes may remain after iron repletion in children; leaves open whether long-term surveillance improves outcomes.
Case-Control (n=69)
Does treatment of iron deficiency anemia improve subclinical biventricular dysfunction in children?
Treatment of iron deficiency anemia in children improves subclinical biventricular dysfunction as assessed by advanced echocardiography, though some subtle alterations may persist.
Zorlu et al. (2026) conducted a case-control in iron deficiency anemia (n=69). Iron deficiency anemia vs. Healthy controls was evaluated on biventricular function assessed by two-dimensional speckle-tracking echocardiography and tissue Doppler imaging. Treatment of iron deficiency anemia in children improved left and right ventricular longitudinal strain and tissue Doppler parameters, though some subtle myocardial alterations persisted.