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July 8, 2026Journal of Clinical MedicineOpen Access

Management of Infected, Non-Responsive Atopic Dermatitis in a Romanian Center

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Authors

RMRaluca‐Gabriela MiulescuIRIoana RoșcaAPAlexandru Pavel

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Overview

Observational study characterizes microbiological profiles and treatment outcomes in children with resistant atopic dermatitis, suggesting significant clinical improvements.

Key Points

  • This study aims to characterize the microbiological profile and evaluate clinical outcomes of individualized treatment in pediatric atopic dermatitis.
  • Observational analytical study with 41 children with infected, treatment-resistant atopic dermatitis.
  • Skin cultures analyzed for antibiotic and antifungal sensitivity.
  • Clinical outcomes assessed using POEM and SCORAD scores at baseline, 7 days, and 30 days.
  • Staphylococcus aureus was the predominant pathogen identified in skin cultures.
  • POEM and SCORAD scores improved significantly over 30 days (p<0.05).
  • Baseline disease severity was the strongest predictor of clinical improvement after 30 days.

Cite This Study

Miulescu et al. (2026) studied this question.

synapsesocial.com/papers/6a4de804d2ea289ef6282eaehttps://doi.org/10.3390/jcm15135248
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Skin Microbiome Under Topical and Systemic Therapeutics in Atopic Dermatitis, a Cross‐Sectional Analysis From <scp>ProRaD</scp>2025
  2. 2Clinical Outcomes Following Personalized Gut Microbiota-Targeted Therapy in Children with Atopic Dermatitis and Laboratory-Confirmed Dysbiosis: A Single-Arm Prospective Pilot Study2026
  3. 3Novel Therapeutic Approaches for Treating Moderate-to-Severe Atopic Dermatitis in Infants with Polyvalent Allergic Sensitisation.2026
  4. 4Individualized Nutritional and Microbiome-Oriented Management of Food Allergy-Associated Atopic Dermatitis in Children: A Prospective Real-World Observational Cohort Study2026
  5. 5Features of the microbial landscape of the skin of patients with atopic dermatitis during exacerbation and in the remission phase2026