Key result
The FMD Asia-1 TUR 11 vaccine provided moderate protection against clinical disease (VE 69%; 95% CI 50-81%) and infection (VE 63%), whereas the Shamir vaccine did not provide adequate protection.
Why the study?
Does FMD Asia-1 vaccination reduce clinical disease and infection in cattle?
Population
1230 cattle >4 months of age across 12 villages in Turkey
Comparison
FMD Asia-1 vaccines vs Unvaccinated cattle with similar virus exposure…
Design
Cohort
Authors
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May warrant TUR 11 preference in Asia-1 outbreaks; leaves open randomized confirmation before policy change.
Observational (n=1,230)
Yes
Does FMD Asia-1 vaccination reduce clinical disease and infection in cattle?
Effect estimate: VE 69% (95% CI 50-81)
The FMD Asia-1 TUR 11 vaccine provides moderate protection against clinical disease and infection in cattle, but vaccination alone may be insufficient to control FMD without additional measures.
Knight-Jones et al. (2014) conducted an observational in Foot-and-mouth disease (n=1,230). FMD Asia-1 vaccines (TUR 11 and Shamir) vs. Unvaccinated cattle was evaluated on Clinical disease (VE 69%, 95% CI 50-81). The FMD Asia-1 TUR 11 vaccine provided moderate protection against clinical disease (VE 69%; 95% CI 50-81%) and infection (VE 63%), whereas the Shamir vaccine did not provide adequate protection.
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