Efficacy of a high-potency multivalent foot-and-mouth disease virus vaccine in cattle against heterologous challenge with a field virus from the emerging A/ASIA/G-VII lineage

Waters et al. (2018) studied Foot-and-mouth disease (n=18). Polyvalent FMD vaccine (A-SAU-95 and A-IRN-05) vs. Unvaccinated controls was evaluated on Protection against developing at least one foot lesion. A polyvalent FMD vaccine provided only 56.3% protection in cattle challenged with the emerging A/ASIA/G-VII lineage field virus, with both unvaccinated controls developing generalized FMD.