Key result
Lone atrial fibrillation is associated with annular dilatation of both mitral and tricuspid valves, but the annular dilatation and valvular regurgitation are significantly greater in the tricuspid valve.
Why the study?
Does lone atrial fibrillation cause significant annular dilatation and valvular regurgitation in the mitral and tricuspid valves?
Population
31 consecutive patients with lone atrial fibrillation (AF) and 28 normal controls (total n=59).
Comparison
Lone atrial fibrillation (exposure) vs Normal controls without atrial fibrillation
Design
Case-control
Authors
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Lone AF was associated with mitral/tricuspid annular dilatation and regurgitation; leaves open whether rhythm control alters progression.
Observational (n=59)
No
Does lone atrial fibrillation cause significant annular dilatation and valvular regurgitation in the mitral and tricuspid valves?
Absolute Event Rate: 12% vs 7.5%
p-value: p=<0.01
Lone atrial fibrillation is associated with annular dilatation of both atrioventricular valves, but the dilatation and resulting regurgitation are significantly more pronounced in the tricuspid valve.
Zhou et al. (2002) conducted an observational in Lone Atrial Fibrillation (n=59). Lone Atrial Fibrillation vs. Normal controls without cardiovascular disease was evaluated on Tricuspid annular area (cm2) (p=<0.01). Lone atrial fibrillation is associated with annular dilatation of both mitral and tricuspid valves, but the annular dilatation and valvular regurgitation are significantly greater in the tricuspid valve.
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