Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 9, 2026Infection Genetics and EvolutionOpen Access

Molecular characterization of circulating mumps virus in Kerala, 2024–2025

View Full Paper
Ask AI
Bookmark
Share

Authors

SNSruthi NhavilthodiRARamaraju AmbatiDDDibu Divakaran

Discussion

Loading...

Member takes

Overview

Randomized trial evaluates mumps virus genotype C in children and adolescents, highlighting vaccine implications.

Key Points

  • This research aims to characterize the molecular features of circulating mumps virus strains in Kerala and assess their implications for public health and vaccination policies.
  • Evaluated 197 suspected mumps cases from March 2024 to March 2025 at the SL-VRDL in Kerala.
  • Confirmed 58 cases using quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis.
  • Conducted whole-genome sequencing on ten selected low-Ct clinical samples to analyze genomic divergence.
  • Identified four high-quality near-complete genomes of MuV, all classified as genotype C.
  • Revealed divergence of these genomes from the L-Zagreb vaccine strain (genotype N) with several amino acid changes in key glycoproteins.
  • Emphasized the necessity for ongoing molecular surveillance and evaluation of the National Immunization Programme regarding mumps-containing vaccines.

Cite This Study

Nhavilthodi et al. (2026) studied this question.

synapsesocial.com/papers/6a55688d4c46ce2df73f3ddehttps://doi.org/10.1016/j.meegid.2026.105987
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular characterization of Mumps virus circulating in Odisha in 20242025 · 1 citations
  2. 2Molecular characterization of Mumps virus genotype C detected from Dibrugarh district of Assam, India2024 · 1 citations
  3. 3Genetic characteristics of mumps viruses isolated in Korea from 2007 to 20122016 · 7 citations
  4. 4Mumps virus (Paramyxoviridae: Orthorubulavirus: Mumps orthorubulavirus) genotyping as a component of laboratory confirmation of infection2023 · 2 citations
  5. 5Epidemiological and molecular analysis of the first outbreak caused by genotype C mumps virus in China2026