Key result
Patients with congestive heart failure had significantly less epicardial fat mass assessed volumetrically by CMR compared with healthy controls (51 g vs. 65 g, p=0.01).
Why the study?
Does volumetric assessment of epicardial adipose tissue using CMR provide a more reproducible measure of epicardial fat compared to one-dimensional thickness measurements in patients with heart failure and healthy controls?
Observational (n=71)
Does volumetric assessment of epicardial adipose tissue using CMR provide a more reproducible measure of epicardial fat compared to one-dimensional thickness measurements in patients with heart failure and healthy controls?
Absolute Event Rate: 51% vs 65%
p-value: p=0.01
Volumetric assessment of epicardial fat mass using CMR is feasible and offers superior reproducibility compared to conventional one-dimensional thickness measurements.
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Lower epicardial fat mass in heart failure was associated with disease status; hypothesis-generating for adipose remodeling and requires prospective validation before clinical use.
Flüchter et al. (2007) conducted an observational in Congestive heart failure (n=71). Congestive heart failure vs. Healthy controls was evaluated on Epicardial fat mass (p=0.01). Patients with congestive heart failure had significantly less epicardial fat mass assessed volumetrically by CMR compared with healthy controls (51 g vs. 65 g, p=0.01).
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