Key result
Symptomatic postural hypotension in the elderly was driven by an orthostatic reduction or failure to rise in peripheral resistance in 83% of cases during postural stress.
Why the study?
What is the haemodynamic mechanism underlying postural hypotension in the elderly during postural stress?
Observational (n=45)
What is the haemodynamic mechanism underlying postural hypotension in the elderly during postural stress?
Postural hypotension in the elderly is primarily driven by a failure to increase peripheral resistance during postural stress, a mechanism that normalizes with appropriate medical management or withdrawal of offending drugs.
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Blunted postural responses in elderly may require age-adjusted tilt norms; leaves open mechanisms in symptomatic hypotension.
Williams et al. (1985) conducted an observational in Postural hypotension (n=45). Symptomatic postural hypotension vs. Cardiovascular-normal elderly patients was evaluated on Orthostatic reduction or failure to rise of peripheral resistance. Symptomatic postural hypotension in the elderly was driven by an orthostatic reduction or failure to rise in peripheral resistance in 83% of cases during postural stress.
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