Key result
The anticardiolipin test for diagnosing antiphospholipid syndrome is subject to variability, but semi-quantitative measures and validated ELISA kits may improve reproducibility.
Design
Review
Authors
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Low-positive anticardiolipin results lack specificity for APS; leaves open need for refined thresholds and assay standardization.
Semi-quantitative measurement or validated ELISA kits are recommended for anticardiolipin testing due to inherent variability in precise quantitative assays.
Harris et al. (2002) conducted a review in antiphospholipid syndrome (APS). anticardiolipin test was evaluated. The anticardiolipin test for diagnosing antiphospholipid syndrome is subject to variability, but semi-quantitative measures and validated ELISA kits may improve reproducibility.
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