March 1, 1995Cancer
Frequent incidence of extrapulmonary sites of initial metastasis in patients with liposarcoma
Key result
Initial extrapulmonary metastasis occurred in 59% of liposarcoma patients and was associated with a significantly longer disease-free interval compared to initial pulmonary metastasis (P=0.001).
Population
60 patients with liposarcoma treated at the Massachusetts General Hospital from 1971 to 1990
Design
Cohort
Authors
Discussion
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Implication
Initial extrapulmonary metastases associate with longer DFI in liposarcoma; hypothesis-generating for tailored surveillance pending prospective validation.
Study Design
Type
Cohort (n=60)
Multicenter
No
Structured PICO
P
Population
60 patients with liposarcoma treated at a single center between 1971 and 1990.
O
Outcome
Frequency of initial extrapulmonary metastasishard clinical
Main Result
p-value: p=0.001
Patients with liposarcoma frequently present with initial extrapulmonary metastases, which are associated with a longer disease-free interval than pulmonary metastases.
Cite This Study
Cheng et al. (1995) conducted a cohort in Liposarcoma (n=60). Initial extrapulmonary metastasis vs. Initial pulmonary metastasis was evaluated on Disease free interval from diagnosis to first metastasis (p=0.001). Initial extrapulmonary metastasis occurred in 59% of liposarcoma patients and was associated with a significantly longer disease-free interval compared to initial pulmonary metastasis (P=0.001).