Key result
Higher aerobic capacity linked to ~1-bpm lower stress heart rate per unit V̇O2 peak increase.
Why the study?
It remains unclear whether the stress-buffering effect of higher fitness on endocrine and autonomic responses depends on the type of acute stressor.
Does aerobic capacity (V̇O2 peak) modulate psychophysiological responses (heart rate, cortisol, and subjective stress) to different types of acute stress paradigms (TSST vs MAST) in healthy adults?
RCT (n=59)
Single-blind
Randomly allocated and counterbalanced order, stratified by sex
No
Does aerobic capacity (V̇O2 peak) modulate psychophysiological responses (heart rate, cortisol, and subjective stress) to different types of acute stress paradigms (TSST vs MAST) in healthy adults?
Higher aerobic fitness is associated with attenuated heart rate reactivity during acute stressful situations, indicating a general cardiovascular advantage independent of the stressor type.
Answers are grounded in this paper and cite their sources.
Aerobic fitness may buffer heart rate during acute stress; extends limited observational data but leaves causal effects open for randomized trials.
Prior evidence suggests that individuals with higher fitness exhibit attenuated endocrine and autonomic responses to acute psychological and physical stressors. However, it remains unclear whether this stress‐buffering effect depends on the type of stressor. This study examined whether aerobic capacity modulates psychophysiological responses to two stress‐induction paradigms (Trier Social Stress Tests, TSST; Maastricht Acute Stress Test, MAST). We hypothesized that fitter participants show lower stress reactivity, with stronger attenuation expected for the MAST, which includes a physical stress component. Healthy participants ( n = 59; 28 women; age: 27.1 ± 5.5 years) completed the TSST and MAST on separate days under standardized conditions. We assessed self‐reported stress, salivary hormones (cortisol, cortisone, DHEAS), and autonomic cardiac regulation (heart rate and root mean square of successive differences of heart periods). Aerobic fitness was determined via graded exercise testing (peak oxygen uptake; V̇O 2 peak: 50.4 ± 8.6 mL/kg/min). Multilevel regression models were used to examine the associations between V̇O 2 peak and stress responses. Higher V̇O 2 peak was significantly associated with lower heart rate across both stress‐induction paradigms (b = 0.99 bpm, p = 0.002). For other outcomes, no significant association with V̇O 2 peak was found. The associations did not differ between TSST and MAST. Aerobic fitness was linked to lower heart rate during the experimental sessions, indicating a modest cardiovascular advantage under acute stress. Contrary to our hypothesis, this effect did not differ between the two stress paradigms, suggesting that the influence of fitness was not specific to the type of stressor. Aerobic capacity, therefore, seems to reduce cardiovascular load during stressful situations in a general manner.
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Raidl et al. (2026) conducted an RCT in Healthy adults (n=59). Higher aerobic capacity (V̇O2 peak) vs. Lower aerobic capacity was evaluated on Heart rate response during acute stress-induction paradigms (b = 0.99 bpm reduction per 1 mL/kg/min change in V̇O2 peak, 95% CI 0.98-1.00, p=0.002). Higher aerobic capacity was significantly associated with a lower absolute heart rate across both psychosocial and physical stress-induction paradigms, with a reduction of 0.99 bpm for each 1 mL/kg/min increase in V̇O2 peak.
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