Key result
Signal transduction mechanisms controlling cardiac contractility undergo significant alterations in patients with chronic heart failure.
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Altered signaling in heart failure should not yet guide therapy; leaves open mechanistic targets for future trials.
Otto-Erich Brodde, Martin C. Michel, Hans-Reinhard Zerkowski; Signal transduction mechanisms controlling cardiac contractility and their alterations in chronic
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Brodde et al. (1995) studied this question. Signal transduction mechanisms controlling cardiac contractility undergo significant alterations in patients with chronic heart failure.
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