Key result
In experimental animal models, hereditary cardiomyopathy depressed contractile performance and altered biochemistry, while diabetic cardiomyopathy significantly altered the relaxation process.
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May guide preclinical therapy targets in genetic cardiomyopathy; leaves open translation of diabetes model findings to patients.
Strobeck et al. (1979) studied Hereditary and acquired cardiomyopathies. Hereditary and acquired cardiomyopathies vs. Age-matched controls (for diabetic model) was evaluated on Mechanical, biochemical, and structural features. In experimental animal models, hereditary cardiomyopathy depressed contractile performance and altered biochemistry, while diabetic cardiomyopathy significantly altered the relaxation process.
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