Key result
Intensive glucose control in type 2 diabetes is linked to persistent long-term legacy benefits.
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Randomized trial shows legacy effect of intensive glucose control in type 2 diabetes, suggesting long-term benefits after intervention ends.
The United Kingdom Prospective Diabetes Study (UKPDS) continues to produce important evidence concerning the evolution of type 2 diabetes and its management. Two studies published in this issue of the Journal provide some answers to two questions of fundamental importance to patients with diabetes and to physicians alike. In one article, Holman et al. (UKPDS 80)1 provide data that confirm a so-called legacy effect associated with intensive glucose control in patients with type 2 diabetes, long after the cessation of randomized intervention. This finding provides a fitting parallel to the observations of the Diabetes Control and Complications Trial/Epidemiology of Diabetes . . .
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Chalmers et al. (2008) conducted an editorial in Type 2 diabetes. Intensive glucose control was evaluated. Intensive glucose control in patients with type 2 diabetes was associated with a legacy effect long after the cessation of randomized intervention.
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