Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 22, 2021Scientific ReportsOpen Access

Variations in the oral microbiome are associated with depression in young adults

View Full Paper
Ask AI
Bookmark
Share

Authors

BWBenjamin WingfieldCLCoral LapsleyAMAndrew McDowell

Discussion

Loading...

Member takes

Overview

Examines how variations in the oral microbiome relate to depression in young adults, suggesting potential implications for mental health.

Key Points

  • This research aims to explore the relationship between the oral microbiome and depression in young adults.
  • Analyzed the salivary microbiome using 16S rRNA gene-based next generation sequencing in 40 depressed young adults and 43 matched controls.
  • Assessed alpha and beta diversity of the salivary microbiome among cohorts.
  • Observed significant differences in alpha and beta diversity between depressed individuals and healthy controls.
  • Identified 21 bacterial taxa differentially abundant in the depressed cohort, including increased Neisseria spp. and Prevotella nigrescens.
  • 19 taxa showed decreased abundance in depressed individuals.

Cite This Study

Wingfield et al. (2021) studied this question.

synapsesocial.com/papers/6a628a10fcd714155f09757fhttps://doi.org/10.1038/s41598-021-94498-6
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The association of depression and oral microbiota2025 · 2 citations
  2. 2Altered oral microbiome composition in mental disorders: a systematic review and meta-analysis2025 · 9 citations
  3. 3Probing the oral-brain connection: Oral microbiome patterns in a large community cohort with anxiety, depression, and trauma symptoms, and periodontal outcomes2024 · 1 citations
  4. 4Sex differences in oral microbiome diversity and depression2026
  5. 5Association Between Oral Dysbiosis and Depression: A Systematic Review2025