Key result
Rat intestinal epithelial cells synthesize at least two intracellular forms of HDL particles, including one containing apoB and another containing apoA-I and apoA-IV.
Population
Rat intestinal epithelial cells (enterocytes)
Design
Preclinical
Authors
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Intestinal HDL isolation in rats supports secretory origin; leaves open contribution to human plasma levels and CV risk.
Demonstrates the existence of at least two distinct intracellular forms of HDL in rat enterocytes, supporting their secretory origin.
Magun et al. (1985) studied Healthy (animal model). Intestinal epithelial cell isolation and fractionation was evaluated on Identification and characterization of intracellular HDL particles. Rat intestinal epithelial cells synthesize at least two intracellular forms of HDL particles, including one containing apoB and another containing apoA-I and apoA-IV.
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