Key result
Sympathetic and parasympathetic neuropathy were frequent in both type 1 and type 2 diabetes, but nerve functions correlated only in type 1 patients (rs=0.525; P=0.0002).
Why the study?
What is the frequency and correlation of sympathetic and parasympathetic neuropathy in type 1 versus type 2 diabetic patients?
Population
60 diabetic patients (43 with type 1 diabetes and 17 with type 2 diabetes)
Comparison
Assessment of sympathetic nerve function and… vs Comparison between type 1 and type 2 diabetic…
Design
Cross-sectional
Authors
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Suggests distinct autonomic neuropathy profiles by diabetes type; leaves open prognostic value and need for prospective validation.
Cross-Sectional (n=60)
What is the frequency and correlation of sympathetic and parasympathetic neuropathy in type 1 versus type 2 diabetic patients?
Sympathetic and parasympathetic neuropathy are frequent in both type 1 and type 2 diabetes, but their correlation differs between the two types, likely due to more severe parasympathetic impairment in type 2 diabetes.
Freccero et al. (2004) conducted a cross-sectional in Type 1 and Type 2 diabetes (n=60). Type 1 diabetes vs. Type 2 diabetes was evaluated on Abnormal sympathetic (VAC index) and parasympathetic (E/I ratio) nerve function. Sympathetic and parasympathetic neuropathy were frequent in both type 1 and type 2 diabetes, but nerve functions correlated only in type 1 patients (rs=0.525; P=0.0002).
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