Key result
Parasympathetic neuropathy in Type 2 diabetic patients was associated with elevated fasting plasma C-peptide (P<0.001) and triglyceride levels (P<0.05) compared to those without neuropathy.
Why the study?
Is parasympathetic neuropathy associated with features of the insulin resistance syndrome in Type 2 diabetic patients?
Population
82 Type 2 diabetic patients (age 63+/-years) evaluated 5 years after diagnosis of diabetes.
Comparison
Presence of parasympathetic neuropathy vs Absence of parasympathetic neuropathy
Design
Cross-sectional
Authors
Loading...
Association with insulin resistance features in T2D neuropathy should not change practice; hypothesis-generating, needs prospective confirmation.
Cross-Sectional (n=82)
Is parasympathetic neuropathy associated with features of the insulin resistance syndrome in Type 2 diabetic patients?
p-value: p=<0.001
Autonomic neuropathy 5 years after the diagnosis of Type 2 diabetes is associated with an unfavorable metabolic risk profile, specifically hyperinsulinemia and hypertriglyceridemia.
Gottsater et al. (1999) conducted a cross-sectional in Type 2 diabetes (n=82). Parasympathetic neuropathy vs. Patients without parasympathetic neuropathy was evaluated on Fasting plasma C-peptide and triglyceride levels (p=<0.001). Parasympathetic neuropathy in Type 2 diabetic patients was associated with elevated fasting plasma C-peptide (P<0.001) and triglyceride levels (P<0.05) compared to those without neuropathy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: