Key result
Ulcerative colitis was associated with vagal autonomic neuropathy in 35% of patients, characterized by a significantly lower E/I ratio compared to healthy controls.
Why the study?
Is autonomic nerve dysfunction present in patients with ulcerative colitis compared to healthy controls and patients with other bowel diseases?
Cross-Sectional (n=154)
Is autonomic nerve dysfunction present in patients with ulcerative colitis compared to healthy controls and patients with other bowel diseases?
Autonomic neuropathy, specifically vagal nerve dysfunction, is common in patients with ulcerative colitis regardless of disease activity or previous colectomy.
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Vagal neuropathy may warrant monitoring in ulcerative colitis; leaves open its prognostic and therapeutic significance.
Lindgren et al. (1993) conducted a cross-sectional in Ulcerative Colitis (n=154). Ulcerative colitis vs. Healthy controls, Crohn's disease, and irritable bowel syndrome was evaluated on Autonomic neuropathy (AN). Ulcerative colitis was associated with vagal autonomic neuropathy in 35% of patients, characterized by a significantly lower E/I ratio compared to healthy controls.
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