Key result
Baroreflex activation therapy significantly reduced mean central aortic blood pressure from 109.7 to 97.4 mm Hg (P<0.01) at 6 months in patients with resistant hypertension.
Why the study?
Does baroreflex activation therapy improve central hemodynamics and arterial stiffness in patients with resistant hypertension?
Population
25 patients with resistant hypertension
Design
Cohort
Follow-up
6 months
Authors
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BAT may improve central hemodynamics in resistant hypertension; hypothesis-generating pending randomized trials.
Does baroreflex activation therapy improve central hemodynamics and arterial stiffness in patients with resistant hypertension?
Absolute Event Rate: 97.4% vs 109.7%
p-value: p=<0.01
Baroreflex activation therapy significantly reduces central blood pressure and arterial stiffness in patients with resistant hypertension, potentially lowering cardiovascular risk.
Wallbach et al. (2014) studied resistant hypertension (n=25). baroreflex activation therapy vs. baseline was evaluated on mean central aortic blood pressure (p=<0.01). Baroreflex activation therapy significantly reduced mean central aortic blood pressure from 109.7 to 97.4 mm Hg (P<0.01) at 6 months in patients with resistant hypertension.
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