Key result
Parental diabetes was associated with sympathovagal imbalance in non-diabetic offspring, characterized by increased sympathetic and decreased parasympathetic activity.
Why the study?
Does parental diabetes affect cardiac autonomic functions in non-diabetic offspring?
Case-Control (n=100)
No
Does parental diabetes affect cardiac autonomic functions in non-diabetic offspring?
Non-diabetic offspring of diabetic parents demonstrate early subclinical sympathovagal imbalance, highlighting a potential increased cardiovascular risk.
May signal early autonomic imbalance in offspring of diabetics; hypothesis-generating and should not yet change practice.
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Mufti et al. (2018) conducted a case-control in Autonomic imbalance (n=100). Parental diabetes vs. Non-diabetic parents was evaluated on Cardiac autonomic functions (sympathovagal imbalance). Parental diabetes was associated with sympathovagal imbalance in non-diabetic offspring, characterized by increased sympathetic and decreased parasympathetic activity.
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