Key result
Percutaneous pulmonary valve implantation with routine bare metal prestenting significantly reduced peak right ventricular outflow tract gradient from 80.6 to 38.8 mm Hg (P=0.001).
Why the study?
Does percutaneous pulmonary valve implantation with routine prestenting with a bare metal stent improve hemodynamics and clinical status in patients with repaired congenital heart disease and homograft dysfunction?
Population
10 patients with repaired congenital heart disease and homograft dysfunction, mean age 26.8±4.0 years, 60%…
Design
Cohort
Follow-up
6 months
Authors
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Supports feasibility of routine BMS prestenting in PPVI; leaves open durability and need for prospective trials.
Observational (n=10)
Does percutaneous pulmonary valve implantation with routine prestenting with a bare metal stent improve hemodynamics and clinical status in patients with repaired congenital heart disease and homograft dysfunction?
Absolute Event Rate: 38.8% vs 80.6%
p-value: p=0.001
PPVI with routine prestenting using a bare metal stent is safe and effective for relieving RVOT obstruction and restoring pulmonary valve competence in patients with repaired congenital heart disease.
Demkow et al. (2010) conducted an observational in Repaired congenital heart disease with homograft dysfunction (n=10). Percutaneous pulmonary valve implantation (PPVI) with routine prestenting with a bare metal stent (BMS) vs. Pre-implantation baseline was evaluated on Peak right ventricular outflow tract (RVOT) gradient (p=0.001). Percutaneous pulmonary valve implantation with routine bare metal prestenting significantly reduced peak right ventricular outflow tract gradient from 80.6 to 38.8 mm Hg (P=0.001).