October 21, 2010Heart
Pre-stenting with a bare metal stent before percutaneous pulmonary valve implantation: acute and 1-year outcomes
Key result
Pre-stenting with a bare metal stent before PPVI was associated with a reduced risk of developing PPVI stent fractures compared to PPVI alone (HR 0.35; 95% CI 0.14-0.87; p=0.024).
Why the study?
Does pre-stenting with a bare metal stent before PPVI reduce stent fractures and improve outcomes in patients with congenital heart disease?
Population
108 consecutive patients with congenital heart disease undergoing percutaneous pulmonary valve implantation
Comparison
Pre-stenting with a bare metal stent before… vs Percutaneous pulmonary valve implantation alone
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
May support pre-stenting before PPVI to lower fracture risk; leaves open confirmation in randomized trials.
Study Design
Type
Cohort (n=108)
Multicenter
No
Structured PICO
Does pre-stenting with a bare metal stent before PPVI reduce stent fractures and improve outcomes in patients with congenital heart disease?
P
Population
108 consecutive patients with congenital heart disease undergoing percutaneous pulmonary valve implantation, followed for 1 year.
E
Exposure
Pre-stenting with a bare metal stent (BMS) before percutaneous pulmonary valve implantation (PPVI)
C
Comparator
Percutaneous pulmonary valve implantation (PPVI) alone
O
Outcome
Procedural complication rates, haemodynamic outcomes, and incidence of PPVI stent fractures at 1 yearcomposite
Main Result
Hazard Ratio: 0.35 (95% CI 0.14–0.87)
Absolute Event Rate: 18% vs 31%
p-value: p=0.024
Pre-stenting with a bare metal stent before percutaneous pulmonary valve implantation is safe and significantly reduces the risk of subsequent stent fractures.
Cite This Study
Nordmeyer et al. (2010) conducted a cohort in Congenital heart disease requiring percutaneous pulmonary valve implantation (n=108). Pre-stenting with a bare metal stent (BMS) vs. Percutaneous pulmonary valve implantation (PPVI) alone was evaluated on PPVI stent fractures (HR 0.35, 95% CI 0.14 to 0.87, p=0.024). Pre-stenting with a bare metal stent before PPVI was associated with a reduced risk of developing PPVI stent fractures compared to PPVI alone (HR 0.35; 95% CI 0.14-0.87; p=0.024).