Key result
An orthostatic systolic blood pressure increase of ≥20 mmHg is rare (0.6% prevalence) in young adults with stage-1 hypertension, and the orthostatic response is negatively associated with supine BP.
Why the study?
To investigate the prevalence of orthostatic hypertension and how BP level, supine BP decline, and the white-coat effect associate with the orthostatic pressor response.
Population
1275 young-to-middle-age individuals with stage-1 hypertension
Design
Observational study
Follow-up
3 months
Authors
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Orthostatic hypertension appears rare in stage-1 hypertension; observational data leave open the prognostic value of orthostatic BP responses.
Observational (n=1,275)
Yes
Orthostatic hypertension (systolic BP increase ≥ 20 mmHg) is rare (0.6%) in young-to-middle-age adults with stage-1 hypertension, but the blood pressure response to standing is significantly influenced by supine BP levels and the white-coat effect.
Palatini et al. (2023) conducted an observational in Stage-1 hypertension (n=1,275). Standing (orthostatic stress) vs. Supine position was evaluated on Prevalence of orthostatic hypertension (systolic BP increase ≥ 20 mmHg). An orthostatic systolic blood pressure increase of ≥20 mmHg is rare (0.6% prevalence) in young adults with stage-1 hypertension, and the orthostatic response is negatively associated with supine BP.
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