Why the study?
The prognostic significance and mechanisms of blood pressure hyperreactivity to standing remain controversial.
Does blood pressure hyperreactivity to standing predict major adverse cardiovascular and renal events in young hypertensive patients?
Population
1207 untreated subjects screened for stage I hypertension (mean age 33.1±8.6 years)
Comparison
Hyperreactivity to standing vs normoreactivity
Design
Cohort study
Follow-up
17.2-year
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Orthostatic hyperreactivity may flag higher-risk young hypertensives; leaves open whether it warrants targeted intervention or changes practice.
Does blood pressure hyperreactivity to standing predict major adverse cardiovascular and renal events in young hypertensive patients?
In young hypertensive patients, an exaggerated systolic blood pressure response to standing is an independent predictor of major adverse cardiovascular and renal events over a 17.2-year follow-up.
A 2022 study studied this question.
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