Key result
Hypersympathicotonic orthostatic response linked to ~14-fold higher 5-year risk of arterial hypertension in young adults.
Why the study?
The role of orthostatic test in predicting arterial hypertension development in young adults was not established.
Does an active orthostatic test predict the development of arterial hypertension in young adults?
Cohort (n=842)
No
Does an active orthostatic test predict the development of arterial hypertension in young adults?
Odds Ratio: 13.6 (95% CI 10–18.7)
p-value: p=<0.001
A hypersympathicotonic response to an active orthostatic test is an independent predictor of arterial hypertension development over 5 years in young adults.
No takes yet. Share an insight, caveat, or question.
Should not yet change practice; leaves open prospective validation of orthostatic testing for hypertension risk stratification in young adults.
E. V. Sklyannaya (2018) conducted a cohort in Arterial hypertension risk (n=842). Hypersympathicotonic orthostatic response vs. Non-hypersympathicotonic orthostatic response was evaluated on Development of arterial hypertension (OR 13.6, 95% CI 10.0-18.7, p=<0.001). A hypersympathicotonic orthostatic response significantly increased the risk of developing arterial hypertension over 5 years in young adults (OR 13.6).
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