Key result
Serial creatine kinase-MBmass measurements on admission and at 7 hours ruled out acute myocardial infarction with 99% sensitivity (95% CI 98-100%) and 96% specificity (95% CI 93-98%).
Why the study?
Do serial creatine kinase-MBmass measurements on admission and at 7 h after symptom onset accurately rule out acute myocardial infarction in patients presenting with symptoms of <5-h duration?
Observational (n=470)
Do serial creatine kinase-MBmass measurements on admission and at 7 h after symptom onset accurately rule out acute myocardial infarction in patients presenting with symptoms of <5-h duration?
Serial creatine kinase-MBmass measurements on admission and at 7 hours can effectively rule out acute myocardial infarction in patients presenting within 5 hours of symptom onset.
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Serial CK-MB mass at 7 h may aid early AMI diagnosis; leaves open its incremental value versus high-sensitivity troponin.
Robbert J. de Winter (1999) conducted an observational in Suspected acute myocardial infarction (n=470). Serial creatine kinase-MBmass measurements was evaluated on Diagnosis of acute myocardial infarction. Serial creatine kinase-MBmass measurements on admission and at 7 hours ruled out acute myocardial infarction with 99% sensitivity (95% CI 98-100%) and 96% specificity (95% CI 93-98%).
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