Key result
Low serum IGFBP-1 levels in elderly men were associated with an unfavorable cardiovascular risk profile, correlating inversely with fasting insulin and triglycerides, and positively with HDL cholesterol.
Why the study?
Is serum IGFBP-1 associated with cardiovascular risk factors and insulin resistance in elderly men?
Observational (n=331)
Is serum IGFBP-1 associated with cardiovascular risk factors and insulin resistance in elderly men?
Low serum IGFBP-1 levels in elderly men are associated with an unfavorable cardiovascular risk profile, including insulin resistance and dyslipidemia.
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Low IGFBP-1 associates with CV risk factors in elderly men; leaves open its value as a biomarker pending prospective studies.
Harrela et al. (2000) conducted an observational in Cardiovascular risk (n=331). Serum insulin-like growth factor-binding protein-1 (IGFBP-1) was evaluated on Association with cardiovascular risk factors, insulin resistance, and insulin secretion. Low serum IGFBP-1 levels in elderly men were associated with an unfavorable cardiovascular risk profile, correlating inversely with fasting insulin and triglycerides, and positively with HDL cholesterol.
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