Key result
In NIDDM patients, reduced IGFBP-1 levels were significantly associated with cardiovascular risk factors including elevated BMI (r=-0.37, p<0.01) and blood pressure (r=-0.35, p<0.01).
Population
74 patients with non-insulin dependent diabetes mellitus (NIDDM)
Design
Cross-sectional
Authors
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IGF-II–lipid correlations in NIDDM are hypothesis-generating; leaves open any causal role in macrovascular disease.
Cross-Sectional (n=74)
p-value: p=<0.01
In patients with NIDDM, low IGFBP-1 levels are associated with multiple factors predisposing to atherogenesis, including elevated blood pressure, BMI, and low HDL cholesterol.
Gibson et al. (1996) conducted a cross-sectional in Non-insulin dependent diabetes mellitus (NIDDM) (n=74). Reduced IGFBP-1 levels was evaluated on Association with cardiovascular risk factors (HDL cholesterol, blood pressure, BMI, insulin, proinsulin) (p=<0.01). In NIDDM patients, reduced IGFBP-1 levels were significantly associated with cardiovascular risk factors including elevated BMI (r=-0.37, p<0.01) and blood pressure (r=-0.35, p<0.01).
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