Key result
Systemic sclerosis was not associated with increased arterial stiffness or echocardiographic findings of organ damage when compared to healthy controls.
Why the study?
Vascular damage is a diagnostic landmark in systemic sclerosis, but whether early subclinical cardiovascular damage can be detected using TTE and cfPWV across disease subtypes compared to healthy controls needed evaluation.
Does systemic sclerosis and its subtypes increase arterial stiffness and echocardiographic signs of organ damage compared to healthy controls?
Population
41 patients with limited and diffuse systemic sclerosis and 23 healthy controls
Comparison
Limited vs diffuse systemic sclerosis vs healthy controls
Design
Observational case-control study
Authors
Loading...
TTE and cfPWV may miss subclinical vascular damage in SSc; leaves open need for alternative stratification tools in this population.
Observational (n=64)
Does systemic sclerosis and its subtypes increase arterial stiffness and echocardiographic signs of organ damage compared to healthy controls?
Arterial stiffness (cfPWV) and standard echocardiography do not show increased subclinical cardiovascular damage in systemic sclerosis patients compared to healthy controls.
Avenatti et al. (2021) conducted an observational in Systemic sclerosis (n=64). Systemic sclerosis vs. Healthy controls was evaluated on Subclinical cardiovascular damage (transthoracic echocardiography parameters and carotid femoral pulse wave velocity). Systemic sclerosis was not associated with increased arterial stiffness or echocardiographic findings of organ damage when compared to healthy controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: