Key result
A computationally efficient model using 6 deformation modes accounted for 81% of left ventricular deformation in a healthy case and 64% in a dilated cardiomyopathy case.
Population
Computational model of the left ventricle
Comparison
Models with 8, 23, or 46 deformation modes
Design
Biomechanical simulation and computational modeling study
Authors
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Requires prospective validation before clinical use; leaves open optimization of deformation-mode LV modeling.
A computationally efficient method using deformation modes enables three-dimensional simulations of the cardiac cycle on a clinically relevant time-scale.
Hong et al. (2019) studied Left ventricular dynamics (n=2). Characteristic deformation modes (computational model) vs. Registered MRI displacements (ground truth) was evaluated on Mean displacement error. A computationally efficient model using 6 deformation modes accounted for 81% of left ventricular deformation in a healthy case and 64% in a dilated cardiomyopathy case.
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