Key result
Higher aortic stiffness was associated with increased left ventricular mass (β=3.0±0.8% per SD, P<0.001), independently of pressure.
Why the study?
Is higher aortic stiffness associated with increased left ventricular mass and altered early diastolic filling in older adults?
Population
347 older adults participating in the Age, Gene/Environment Susceptibility-Reykjavik Study
Design
Cross-sectional
Authors
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Aortic stiffness may augment LV load via annular displacement in older adults; leaves open contributions to hypertrophy and diastolic filling.
Cross-Sectional (n=347)
Is higher aortic stiffness associated with increased left ventricular mass and altered early diastolic filling in older adults?
Effect estimate: β=3.0±0.8% per SD
p-value: p=<0.001
Higher aortic stiffness is independently associated with increased LV mass, and impaired diastolic recovery of energy from aortic stretch may contribute to diastolic dysfunction susceptibility in women.
Bell et al. (2015) conducted a cross-sectional in Older adults (n=347). Aortic stiffness was evaluated on Left ventricular mass (β=3.0±0.8% per SD, p=<0.001). Higher aortic stiffness was associated with increased left ventricular mass (β=3.0±0.8% per SD, P<0.001), independently of pressure.
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