What question did this study set out to answer?

This study aims to analyze treatment modalities, survival trends, and prognostic factors for primary central nervous system low-grade B-cell lymphoma.

July 29, 2026Cancer MedicineOpen Access

Survival Outcomes and Prognostic Factors in Patients With Primary Central Nervous System Low‐Grade B‐Cell Lymphoma: A Population‐Based Cohort Study

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Authors

LCLvwen ChenNanjing Medical University LCLei CaoJiangsu Province Hospital YZYuxiao ZhaoTianjin University of Science and Technology

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Implication

Cohort study analyzes treatment trends and survival outcomes in patients with primary central nervous system low-grade lymphoma, suggesting improved prognosis over two decades.

Key Points

This study aims to analyze treatment modalities, survival trends, and prognostic factors for primary central nervous system low-grade B-cell lymphoma.
Patient data were extracted from the SEER database for those diagnosed between 2000 and 2021.
A total of 267 adult patients were included, with analysis divided into two time periods: 2000-2009 and 2010-2021.
Statistical comparisons were made for treatment modalities and survival outcomes across these periods.
The 1-, 5-, and 10-year overall survival rates were 84.3%, 73.4%, and 61.8%, respectively.
Median overall survival improved from 11.25 years in the first period to not reached in the second period (HR 0.46, 95% CI: 0.28-0.74; p = 0.001).
Surgery improved outcomes compared to non-surgical management (HR 0.47, 95% CI: 0.31-0.72, p < 0.001).

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a69a2aec8da07d9defa679e https://doi.org/10.1002/cam4.72147

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Implication

Cohort study analyzes treatment trends and survival outcomes in patients with primary central nervous system low-grade lymphoma, suggesting improved prognosis over two decades.

Survival Outcomes and Prognostic Factors in Patients With Primary Central Nervous System Low‐Grade B‐Cell Lymphoma: A Population‐Based Cohort Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Survival Outcomes and Prognostic Factors in Patients With Primary Central Nervous System Low‐Grade B‐Cell Lymphoma: A Population‐Based Cohort Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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