Key result
Cellular calcium exchange in the heart is highly regulated across multiple compartments, with the regulation of calcium movements consuming approximately 25% of the cell's total energy output.
Population
arterially perfused whole heart and cardiac cells
Design
Review
Authors
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Emphasizes calcium handling as major cardiomyocyte energy sink; leaves open therapeutic targeting in cardiac energetics.
This review details the complex mechanisms of cellular calcium exchange and regulation across cardiac organelles during contraction and relaxation.
G. A. Langer (1992) conducted a review in Cardiac calcium exchange. Cellular calcium exchange in the heart is highly regulated across multiple compartments, with the regulation of calcium movements consuming approximately 25% of the cell's total energy output.
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