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July 1, 2000AJP Heart and Circulatory Physiology

The degree of colocalization of DHPR and RyR in neonatal rabbit ventricular myocytes significantly increased during development from 3 to 20 days of age (P < 0.0005).

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Key result

The degree of colocalization of DHPR and RyR in neonatal rabbit ventricular myocytes significantly increased during development from 3 to 20 days of age (P < 0.0005).

Authors

FSFranklin SedaratLXLiqun XuEMEdwin D.W. Moore

Discussion

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Overview

May refine models of neonatal calcium handling; leaves open translation to human infant cardiac function.

PICO

P
Population
Isolated neonatal rabbit ventricular myocytes aged 3 to 20 days.
E
Exposure / Comparator
Developmental age vs 3-day-old group
O
Primary Outcome
Degree of colocalization of DHPR and RyR, p=< 0.0005

Main Result

p-value: p=< 0.0005

Cite This Study

Sedarat et al. (2000) studied Neonate rabbit heart development. Developmental age vs. 3-day-old group was evaluated on Degree of colocalization of DHPR and RyR (p=< 0.0005). The degree of colocalization of DHPR and RyR in neonatal rabbit ventricular myocytes significantly increased during development from 3 to 20 days of age (P < 0.0005).

synapsesocial.com/papers/6a6a28cd57b5d39462f17867https://doi.org/10.1152/ajpheart.2000.279.1.h202
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