Key result
Patients with maturity-onset diabetes without thromboembolic complications had higher basal AT III biological activity and fibrinolytic activities than controls.
Why the study?
How do haemostatic parameters respond to a venous occlusion test in patients with maturity-onset diabetes mellitus without thromboembolic complications compared to normal subjects?
Population
Patients with maturity-onset diabetes mellitus without thromboembolic complications and apparently normal…
Comparison
Venous occlusion test (VOT) vs Apparently normal subjects of the same age
Design
Case-control
Authors
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Altered haemostasis in diabetes warrants no practice change; leaves open its contribution to thrombotic risk.
Observational
How do haemostatic parameters respond to a venous occlusion test in patients with maturity-onset diabetes mellitus without thromboembolic complications compared to normal subjects?
Patients with maturity-onset diabetes without thromboembolic complications appear to have an activated protective mechanism against intravascular clotting.
Grignani et al. (1981) conducted an observational in Maturity-onset diabetes mellitus. Maturity-onset diabetes mellitus vs. Apparently normal subjects was evaluated on Haemostatic parameters before and after venous occlusion test. Patients with maturity-onset diabetes without thromboembolic complications had higher basal AT III biological activity and fibrinolytic activities than controls.
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