Chronic use of both heat-not-burn cigarettes and traditional combustion cigarettes displayed an adverse phenotype in terms of endothelial function, oxidative stress, and platelet activation.
Observational
Does chronic use of heat-not-burn cigarettes improve endothelial function, oxidative stress, and platelet activation compared to traditional combustion cigarettes in adult smokers?
Heat-not-burn cigarettes do not appear to eliminate the adverse cardiovascular phenotypic effects, such as endothelial dysfunction, oxidative stress, and platelet activation, seen with traditional cigarettes.
Tobacco habit still represents the leading preventable cause of morbidity and mortality worldwide. Heat-not-burn cigarettes (HNBCs) are considered as an alternative to traditional combustion cigarettes (TCCs) due to the lack of combustion and the absence of combustion-related specific toxicants. The aim of this observational study was to assess the effect of HNBC on endothelial function, oxidative stress and platelet activation in chronic adult TCC smokers and HNBC users. The results showed that both HNBC and TCC display an adverse phenotype in terms of endothelial function, oxidative stress and platelet activation. Future randomised studies are strongly warranted to confirm these data.
Loffredo et al. (Mon,) conducted a observational in Tobacco habit. Heat-not-burn cigarettes (HNBCs) vs. Traditional combustion cigarettes (TCCs) was evaluated on Endothelial function, oxidative stress and platelet activation. Chronic use of both heat-not-burn cigarettes and traditional combustion cigarettes displayed an adverse phenotype in terms of endothelial function, oxidative stress, and platelet activation.