March 1, 1987Annual Review of Physiology
Cardiac Muscle Changes in Senescence
Key result
Senescence alters the biophysical and biochemical mechanisms governing cardiac muscle excitation, activation, and contraction.
Population
Cardiac muscle preparations (thin trabeculae or papillary muscles) studied for senescence-related changes
Design
Review
Authors
Discussion
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Implication
Alerts clinicians to senescence-driven cardiac changes; leaves open targeted interventions pending validation.
Structured PICO
P
Population
Cardiac muscle preparations (thin trabeculae or papillary muscles) studied for senescence-related changes
This chapter provides a comprehensive review of the biophysical and biochemical mechanisms underlying age-related changes in cardiac muscle excitation, activation, and contraction.
Cite This Study
Edward G. Lakatta (1987) conducted a review in Cardiac muscle senescence. Senescence was evaluated. Senescence alters the biophysical and biochemical mechanisms governing cardiac muscle excitation, activation, and contraction.