Key result
Pre-eclamptic pregnancies exhibited altered diurnal rhythms of pressor hormones, including significantly lower plasma renin activity and loss of the normal daytime fall in angiotensin II.
Population
31 pregnant women after 26 weeks gestation, including 10 normotensive women, 13 with uncomplicated…
Design
Cross-sectional
Authors
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May prompt ambulatory BP monitoring in pre-eclampsia; leaves open renin-angiotensin roles in diurnal patterns.
Observational (n=31)
Pre-eclampsia is associated with altered diurnal rhythms of pressor hormones, including a failure of angiotensin II and norepinephrine to fall at night, which may contribute to nocturnal hypertension.
Beilin et al. (1983) conducted an observational in Pregnancy (normotensive, hypertensive, and pre-eclamptic) (n=31). Pre-eclampsia and uncomplicated hypertension vs. Normotensive pregnancy was evaluated on Diurnal patterns of blood pressure, plasma renin activity, angiotensin II and catecholamines. Pre-eclamptic pregnancies exhibited altered diurnal rhythms of pressor hormones, including significantly lower plasma renin activity and loss of the normal daytime fall in angiotensin II.
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