Why the study?
What are the circadian patterns of blood pressure and pressor hormones in normal and hypertensive late pregnancy?
Population
31 women in late pregnancy (10 normotensive, 21 hypertensive, including 8 pre-eclamptic)
Design
Cross-sectional
Authors
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Suppressed renin-angiotensin activity in pre-eclampsia may underlie nocturnal hypertension; hypothesis-generating for circadian profiling in late-pregnancy hypertension.
What are the circadian patterns of blood pressure and pressor hormones in normal and hypertensive late pregnancy?
Pre-eclamptic women exhibit suppressed plasma renin activity and angiotensin II, and altered circadian rhythms of pressor hormones may contribute to nocturnal hypertension.
Beilin et al. (1982) studied this question.
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