Key result
The Australian HPeV3 outbreak strain is a recombinant virus that emerged between March 2012 and November 2013, featuring a highly stable capsid encoding region and an evolving nonstructural coding region.
Population
18 Australian cases of human parechovirus type 3 (HPeV3) infection in infants in the period from 2012-2015
Authors
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Alerts clinicians to monitor recombinant HPeV3 in infant outbreaks; leaves open impact of nonstructural evolution on virulence.
Observational (n=18)
The Australian HPeV3 outbreak strain originated from a major recombination event and shows significant evolution in the nonstructural coding region while maintaining a stable capsid encoding region.
Alexandersen et al. (2017) conducted an observational in Human parechovirus type 3 (HPeV3) infection (n=18). HPeV3 infection was evaluated on Phylogenetic and transmission network analysis. The Australian HPeV3 outbreak strain is a recombinant virus that emerged between March 2012 and November 2013, featuring a highly stable capsid encoding region and an evolving nonstructural coding region.
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