Key result
Human parechovirus caused extensive white matter brain injury in a neonate presenting with sepsis-like illness or encephalitis.
Highlights human parechovirus as a potential cause of extensive white matter brain injury in neonates presenting with sepsis-like illness or encephalitis.
Clinicians should consider parechovirus testing in neonates with sepsis-like encephalitis; this case report leaves open questions of incidence and causality.
There is a wide differential for white matter changes on magnetic resonance imaging in an un-well neonate. Human parechovirus is one of the very few neurotropic viruses, which presents with sepsis like illness or encephalitis in neonates and can caus
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Shivamurthy et al. (2015) studied this question. Human parechovirus caused extensive white matter brain injury in a neonate presenting with sepsis-like illness or encephalitis.
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