Key result
Spontaneous contractions in isolated rat myocytes had a significantly lower average shortening velocity compared to rested state twitches (3.74 vs 5.35 microns/s per sarcomere, P<0.01).
Absolute Event Rate: 3.74% vs 5.35%
p-value: p=<0.01
Spontaneous contractions in rat myocytes exhibit slower shortening velocities and different calcium release dynamics compared to electrically triggered rested state twitches.
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SC wave shortening in rat myocytes may alter triggered twitches; leaves open in vivo relevance to Ca2+ handling.
Tameyasu et al. (1994) studied Isolated rat myocytes. Spontaneous contraction (SC) vs. Rested state twitch (RS) was evaluated on Average shortening velocity from onset to peak of shortening (p=<0.01). Spontaneous contractions in isolated rat myocytes had a significantly lower average shortening velocity compared to rested state twitches (3.74 vs 5.35 microns/s per sarcomere, P<0.01).
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